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Cetp polymorphisms

WebAug 27, 2024 · CETP Gene: Another gene related to longevity is the CETP gene (cholesteryl ester transfer protein), which involves exchanging triglycerides with cholesteryl esters. One polymorphism related to …

CETP polymorphisms influence cholesterol metabolism but not …

WebBy contrast, carrier status at the CETP SNP was associated with a reduced risk of myocardial infarction regardless of activity level (hazard ratio, 0.72; 95% confidence interval, 0.57 to 0.92; P-interaction=0.71). No association between LIPC SNP carrier status and myocardial infarction risk was noted. WebSep 26, 2008 · Abstract. Cholesteryl ester transfer protein (CETP) is a component of the high density lipoprotein (HDL). Variations in the CETP gene may cause CETP deficiency, … roly daniels youtube https://asoundbeginning.net

Polymorphism in the CETP gene region, HDL cholesterol, …

WebSep 2, 2024 · The cholesteryl ester transfer protein (CETP) is a protein involved in the transfer of cholesteryl esters between lipoproteins. CETP is a crucial protein involved in the regulation of high density lipoprotein (HDL) levels and may affect susceptibility to age-related diseases, including atherosclerosis and Alzheimer's Disease (AD). WebJun 18, 2024 · The CETP gene is highly polymorphic. Some variants in the CETP gene are associated with decreased plasma CETP protein activity and protein levels, thereby resulting in greater HDL-C concentrations [ 14, 15 ]. Among the CETP polymorphisms, rs708272 has been widely studied. WebFor a common variant in LPL, the impact on myocardial infarction varied by activity level, whereas the effects of a common variant in CETP on myocardial infarction risk did not. … roly cottingham carpets boston

Cholesterol Ester Transfer Protein - an overview - ScienceDirect

Category:Association between Eight Functional Polymorphisms and …

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Cetp polymorphisms

Physical activity modifies the effect of LPL, LIPC, and CETP ...

WebBackground: Polymorphisms in the adenylate cyclase 9 (ADCY9) gene influence the benefits of the cholesteryl ester transfer protein (CETP) modulator dalcetrapib on cardiovascular events after acute coronary syndrome. We hypothesized that Adcy9 inactivation could improve cardiac function and remodeling following myocardial … WebNov 27, 2013 · Cholesteryl ester transfer protein (CETP) is an important regulator of plasma HDL-C. Several genetic mutations in the CETP gene were found to be associated with HDL-C levels. The aim of the present study is to evaluate the association of HDL-C-related CETP polymorphisms and risk of coronary atherosclerosis. Methods

Cetp polymorphisms

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WebJan 23, 2009 · For example, as shown in Table 3, polymorphism at rs708272 in the CETP gene was associated with a per-allele increase in HDL-C levels of 3.1 mg/dL and a … WebWe focused on the single-nucleotide polymorphism with the largest individual effects, CETP (rs5882), and found that increased G-allele dosage was associated with higher fractional anisotropy and lower radial and mean diffusivities in voxel-wise analyses of the whole brain. A follow-up analysis detected white matter associations with rs5882 in ...

WebJun 18, 2024 · There was no link between CETP I450V polymorphism and CHD. Analysis based on hypertensive status showed a significant association between these … WebJan 16, 2010 · A 2006 study I405V polymorphism of the cholesteryl ester transfer protein (CETP) gene in young and very old people reports “We recruited 100 healthy young people (median age 31 years) and 100 very old people (median age 89 years) and analysed their DNA for the presence of I405V polymorphism.

WebJan 13, 2010 · Context Polymorphisms in the cholesteryl ester transfer protein (CETP) gene have been associated with exceptional longevity and lower cardiovascular risk, but … WebJun 24, 2024 · This gene is present as CETP Studies (9) Significant/Non-significant: 4/5 Study 1 Longevity Association Non-significant Population Japanese Study Design Polymorphisms (mutations in intron 14 and exon 15, and Taq1B) were examined in 256 centenarians and 190 healthy younger controls (22-65 years old) Conclusions

WebApr 28, 2024 · Functional interaction between −629C/A, −971G/A and −1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study ...

WebAug 15, 2013 · The I405V polymorphism of the cholesteryl ester transfer protein gene ( CETP) has been suggested to be a protective factor conferring longevity in Ashkenazi Jews, although findings in other races are not supportive. roly ecoWebAbstract. Background: Cholesteryl ester transfer protein (CETP) plays a major role in the metabolism of high-density lipoprotein. Polymorphisms in the CEPT gene can affect susceptibility to atherosclerosis and cardiovascular disease. The aim of this study was to evaluate the association of the CETP I405V polymorphism with ischemic stroke. roly dumpstersWebHigh density lipoprotein (HDL) plays a central role in the removal of excess cholesterol from cells, and cholesteryl ester transfer protein (CETP) is a crucial protein involved in the … roly egerton warburtonWebMar 1, 2014 · Single nucleotide polymorphisms of angiotensin-converting enzyme (ACE) such as rs1799752, nuclear factor kappa B (NFkB) such as rs28362491 and cholesteryl ester transport protein (CETP) such as rs708272 (TaqB1) and rs5882 (I405V) were evaluated in nonagenarians, centenarians, and average life span individuals (controls). … roly eastendersWebCETP polymorphisms are associated with two morphometric measures in females, dependent upon diagnosis and APOE ε4 carrier status. No significant associations were … roly dollyWebAging is an irreversible process that produces the progressive decline of physiological functions favoring the development of cardiovascular complications associated with genetic Risk Alleles (RA). A case-control study using a sample of 90 Venezuelan roly everestWebAnalysis of the rs1532624 polymorphism of CETP showed a relationship between the CC homozygosity and increased risk of CAD in the studied Polish population … roly eastenders dog