Crambene
http://yuxiqbs.cqvip.com/Qikan/Article/Detail?id=1005510485 WebOur previous work has demonstrated that induction of pancreatic acinar cell apoptosis by crambene protects mice against acute pancreatitis. However, little is known about how the induction of apoptosis reduces the severity of acute pancreatitis. Because the clearance of apoptotic cells might suppress inflammation and critically regulate immune ...
Crambene
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WebAcute pancreatitis is a common and refractory inflammatory disease affecting pancreatic acinar cells. The mortality rate is approximately 30%. Cholecystokinin (CCK) -induced acute pancreatitis is the... WebJul 15, 2001 · Crambene and I3C individually caused induction of glutathione S-transferase (GST) and quinone reductase (QR) activity. The mixture of crambene and I3C caused induction of GST and QR that was significantly greater than the sum of the induction by individual treatments. Upregulation of total GST activity was not as great as that of QR, …
WebAug 1, 2001 · Europe PMC is an archive of life sciences journal literature. Rapid isolation and purification of 1-cyano-2-hydroxy-3-butene (crambene) from Crambe abyssinica seed meal using immiscible solvent extraction and high-performance liquid chromatography. WebThe 2D chemical structure image of crambene is also called skeletal formula, which is the standard notation for organic molecules. The carbon atoms in the chemical structure of crambene are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be associated with enough …
WebCrambene leads to induction of apoptosis by protects mice against acute pancreatitis via anti-inflammatory pathways. MedKoo Biosciences, Inc. Tel: +1-919-636-5577 Fax: +1 … WebNov 18, 2009 · Additionally, we evaluated the effect of crambene on quinone reductase activity in Hepa 1c1c7 cells, because this system had been shown to possess high …
WebJul 1, 2004 · Crambene, a nitrile product of the glucosinolate progoitrin, increases hepatic quinone reductase (QR) when included in the diet of animals. Here we evaluate the …
WebCrambene (5 mM) induced quinone reductase activity and caused cell cycle arrest in the G 2 /M phase in mouse Hepa 1c1c7 cells, rat H4IIEC3 cells, and human Hep G2 cells (>95% viability). Doses of crambene needed for induction of quinone reductase in cell culture were ∼100-fold greater than effective doses of sulforaphane. psychological testing and assessment reviewerWebMay 1, 2007 · Crambene was added into these tubes with the varying working concentration of 2 mmol/L. Acini were incubated with or without crambene at 37°C in a shaker water bath for 3 hours. After 3 hours of incubation, the cells were washed three times in buffer A and taken up in 1 ml of 10% FBS. Samples of 20 μl were taken for analysis of … hospitals san bernardino californiaWebCrambene results in the induction of apoptosis by protects mice against acute pancreatitis via anti-inflammatory pathways. hospitals san bernardino caWebJan 1, 2008 · Crambene (CHB), a plant nitrile, induces pancreatic acinar cell apoptosis, mainly through the mitochondrial pathway. However, a role for mitogen-activated protein kinases (MAPKs) in this process ... psychological testing and assessment notesWebApr 1, 1998 · Crambene causes a prolonged elevation of rat hepatic and pancreatic glutathione and induces the GSHS-transferases (GSTs). Because elevated GST activity against the model substrate chlorodinitrobenzene does not reflect individual isoenzyme induction, quantitative HPLC evaluation of specific GST subunits is necessary to fully … psychological testing austin txWebWe investigated the apoptotic pathway activated by crambene (1-cyano-2-hydroxy-3-butene), a plant nitrile, on pancreatic acinar cells. As evidenced by annexin V-FITC staining, crambene treatment for 3 h induced the apoptosis but not necrosis of pancreatic acini. Caspase-3, -8, and -9 activities in acini treated with crambene were significantly higher … psychological testing atlanta gaWebAug 1, 2006 · As evidenced by annexin V-FITC staining, crambene treatment for 3 h induced the apoptosis but not necrosis of pancreatic acini. Caspase-3, -8, and -9 activities in acini treated with crambene were ... psychological testing and assessment book