Webbwhen tested during retrieval session. I demonstrate that the HIPP cells are driven by cholinergic transmission via M1 muscarinic receptors and in this way contribute to the … Webb29 sep. 2024 · Notably, dendritic inhibition driven by HIPP cells can reduce spike generation in BCs (Savanthrapadian et al., 2014). Our study showed that activation of the SuM input reliably excites HIPP and TML cells, which could suppress BCs activities, leading to somatic disinhibition of GCs and enhanced spike generation.

arXiv:2105.06057v1 [q-bio.NC] 13 May 2024

WebbThe shortage of organ donors for regenerative medicine has stimulated research on stem cells as a potential resource for cell-based therapy. Stem cells have been used widely … Each 106 HEK293T cells were grown in DMEM with 10% FCS and each 1% Penicillin and Streptomycin (Life Technologies, Darmstadt, Germany) at 37 °C, 5% CO2. On the day of transfection, fresh DMEM with 25 μM chloroquine was applied and cells further incubated for 2–6 h. When cells had grown to 80% confluence, … Visa mer All mice were bred and raised in the animal facility at the Institute of Biology, Otto-von-Guericke University Magdeburg. The animals were … Visa mer Mice were single-caged 3–4 days before the start of the experiments. Behavioral experiments were conducted during the dark phase, between … Visa mer Lentiviral vectors were based on the vector backbone pLL3.756. First, a dsRed cassette from MSCV-RmFF was used to replace GFP in MSCV … Visa mer AAV hSyn-DIO-hM4Di-mCherry, AAV hSyn-DIO-hM3Dq-mCherry and AAV hSyn-DIO-mCherry were obtained from the Vector Core … Visa mer failed to repair the image database file

Interneurons in the Hippocampal Dentate Gyrus: an In Vivo …

Webb3 aug. 2010 · The mammalian hippocampus, including dentate gyrus (DG) and areas CA3 and CA1, plays an important role in many forms of learning and memory, including the ability to rapidly form memories of unique episodic events ( Eichenbaum, 2000; Kesner et al., 2004; Squire, 1987 ). WebbA 579 bp segment of the 5'-flanking region of this gene was cloned which exhibited robust promoter activity upon transfection in human intestinal epithelial cells. Deletion analysis revealed that the core promoter activity to be embedded in a region between -234 and -23 that lacked TATA element, was GC-rich, and harbored several putative cis-regulatory … Webb4 juni 2015 · Finally, all INs with their axon projection to the outer ML (OML) in this study were classified as HIPP-like cells. Although original description of HIPP cells found the dendrites restricted in the hilus (Han et al. 1993), our recent study (Liu et al. 2014) showed that a large proportion of HIPP-like cells, which project their axons to the OML ... dog on the internet