Web13 apr 2024 · We utilized the JeKo-1 cell line, a CD19-expressing mantle cell lymphoma model (Fig. S10A). To block mitochondrial apoptosis, we generated JeKo-1 variants … Web1 dic 2024 · The JeKo-1-parental cell line, established from PBMCs of a terminal stage MCL patient with a large cell variant of MCL showing leukemic conversion, similar to pt4 used in our study. 16 Interestingly, when the JeKo-1-parental cell line was originally cultured in vitro, multicellular spheroid mode of growth was documented.
U7D-1 is a Selective USP7 PROTAC Degrader For Leukemia Research
Web29 set 2024 · JeKo-1 cell line target antigen-loss model. JeKo-1 CD19 and/or CD20 knock-out (KO) cell lines were mixed at an equal 1:1:1:1 ratio and co-incubated with AdCAR NK-92 cells at an E:T ration of 5:1 ... Web1 apr 2024 · Particularly, U7D-1 shows anti-proliferative activity in p53 wild-type cell lines. Obviously, U7D-1 maintains potent cell growth inhibition in p53 mutant cancer cells. Once again, U7D-1 upregulates the level of p53 and p21 proteins in a time-dependent manner. Interestingly, it induces cleavage of caspase-3 in the Jeko-1 cell line in a time ... cmc カルボキシメチルセルロース 電池
Toledo - CRL-2631 ATCC
Webundertaking xenograft studies with primary cells, we used the MCL cell line JEKO-1 to assess kinetics, disease burden and distribution of MCL cells in NSG mice. JEKO-1 … WebGA induces apoptosis in JeKo- 1 cells but not in normal bone marrow cells, which was involved in reducing the membrane potential of mitochondria, activating caspases-3, -8 and -9 and decreasing the ratio of Bd-2 and Bax without cell cycle arresting. Web24 giu 2013 · This can easily be determined using the same assay platform with fluorescence imaging at multiple wavelengths. For example, a population of Jeko-1 (a CD20-postive cell line) cells was labeled with Cell Tracker green and combined with a population of Jurkat T-leukemia cells (a CD20-negative cell line) that was labeled with … cmczip 解凍できない