Tm4sf5 antibody
WebAntibody: TM4SF5 Rabbit anti-Human Polyclonal (aa112-157) Antibody Application: ELISA Reactivity: Human Format: Unconjugated, Unmodified Other formats: HRP FITC Biotin … WebJan 31, 2024 · The transmembrane 4 L six family member 5 (TM4SF5) is aberrantly expressed in hepatocellular and colorectal cancers, and has been implicated in tumor …
Tm4sf5 antibody
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WebKwon, S; Choi, KC; et al. Monoclonal Antibody Targeting of the Cell Surface Molecule TM4SF5 Inhibits the Growth of Hepatocellular Carcinoma. CANCER RESEARCH 74:3844-3856(2014). CANCER RESEARCH 74:3844-3856(2014). WebTM4SF5 Antibodies TM4SF5 ELISA Kits TM4SF5 Proteins The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.
WebThe cell surface transmembrane 4 superfamily member 5 protein (TM4SF5) has been implicated in various human cancers. Immunization with a peptide vaccine targeting human TM4SF5 has been shown to exert prophylactic and therapeutic effects against the development of hepatocellular carcinoma and colon c … WebNov 29, 2016 · Transmembrane 4 superfamily member 5 protein (TM4SF5) is a potential therapeutic target for hepatocellular carcinoma (HCC) and colon cancer. In a previous study, we demonstrated the prophylactic and therapeutic effects of a TM4SF5-specific peptide vaccine and monoclonal antibody in HCC and colon cancer in a mouse model.
WebJun 8, 2024 · Generation and characterization of novel TM4SF5-targeting antibodies: 5. 주 관 WebAnti-TM4SF4 Antibody Products. Anti-TM4SF4 antibodies are offered by a number of suppliers. This target gene encodes the protein 'transmembrane 4 L six family member 4' in humans and may also be known as ILTMP, il-TMP, transmembrane 4 L6 family member 4, and intestinal and liver (il) tetraspan membrane protein.
WebAug 18, 2024 · TM4SF1 can interact with integrin-ß1 and integrin-α5 via its EC2 domain, and integrins-TM4SF1 protein complexes likely affect cell adhesion and motility ( Hemler, 2005; Shih et al., 2009; Lee et al., 2011 ). The dynamics of TM4SF1 on the plasma membrane play an important role in cell motility.
WebThe protein encoded by the TM4SF5 gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins … nova chartwheelsWebNov 14, 2024 · Vaccination targeting TM4SF5 induced production of anti-TM4SF5 antibodies and suppressed growth of TM4SF5-expressing pancreatic cancer in a mouse model. The cell growth and motility were decreased by treatment with the anti-hTM4SF5 monoclonal antibody in TM4SF5-expressing mouse pancreatic cancer cells in vitro. … nova chat 10 activeWebTM4SF5 protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. ... PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. Antibody HPA055674; ANTIBODY INFORMATION; Provider: Atlas Antibodies Sigma-Aldrich: Product name: … nova care kids st charles ilWebAug 3, 2014 · The expression levels of TM4SF5 mRNA in the indicated human (left) and mouse (right) colon cancer cell lines were analyzed by RT-PCR. B. Effect of anti-TM4SF5 … how to simplify household choresWebTM4SF5 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC applications. TM4SF5 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Acts as a lysosomal membrane arginine sensor (PubMed:30956113). Forms a complex with MTOR and SLC38A9 on lysosomal ... nova charity west islandWebTM4SF5-positive tumors exhibited locally-increased CD44 expression, suggesting tumor cell differentiation; TM4SF5 interacted with CD151, and caused the internalization of CD63 … nova charity wakefieldWebSep 30, 2014 · Therapeutic effect of a TM4SF5-specific monoclonal antibody against colon cancer in a mouse model Authors Young-Eun Kim 1 , Sanghoon Kwon 2 , Guang Wu 2 , Dongbum Kim 3 , Byoung Kwon Park 4 , Jeong-A Park 5 , Kyung-Chan Choi 6 , Doo-Sik Kim 7 , Hyung-Joo Kwon 8 , Younghee Lee 5 Affiliations nova centre prestatyn north wales